ISI Micro

Evaluate many different cell properties and correlate them to identify functional and health problems in your production.

For the histological analysis, evaluating only the villus height and crypt depth may not be enough to analyze if the villus is healthy and functional. The ISI Micro is a metric evaluation methodology of histological parameters that leads to a more complete analysis. In the ISI methodology, 8 parameters in the intestinal villus are evaluated: Lamina propria thickness, Epithelial thickness, Enterocytes proliferation, Inflammatory cell infiltration on epithelium, Inflammatory cell infiltration in lamina propria, Goblet cells proliferation, congestion and the presence of oocytes .The results are highly correlated with the animals’ performance, as demonstrated in scientific publications. Thus, it is a great tool to evaluate precisely the effect of products and practices in the animal intestinal health.

Links to technical works already published:

Effect of aflatoxin experimental ingestion and Eimeira vaccine challenges on intestinal histopathology and immune cellular dynamic of broilers: applying an Intestinal Health Index

Kraieski, A.L., et al., 2017.

Histological parameters to evaluate intestinal health on broilers challenged with Eimeria and Clostridium perfringens with or without enramycin as growth promoter

Belote, B.L. et al., 2018.

Applying I see inside histological methodology to evaluate gut health in broilers challenged with Eimeria

Belote, B.L. et al., 2019.

Growth performance and intestinal health of broilers fed a standard or low-protein diet with the addition of a protease

Cardinal, K.M. et al., 2019.

Protected Blend of Organic Acids and Essential Oils Improves Growth Performance, Nutrient Digestibility, and Intestinal Health of Broiler Chickens Undergoing an Intestinal Challenge

Stefanello, C. et al. 2020.

Basal and Infectious Enteritis in Broilers Under the I See Inside Methodology: A Chronological Evaluation

Sanches et al, 2019.

Field evaluation of feeding spray-dried plasma in the starter period on final performance and overall health of broilers

Belote, B. et al., 2021.

Novel Models for Chronic Intestinal Inflammation in Chickens: Intestinal Inflammation Pattern and Biomarkers

Dal Pont, G. et al. 2021.

Effect of functional oils on the immune response of broilers challenged with Eimeria spp

Andretta, I. et al. 2019.